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0001104659-22-091286
BAKER BROS. ADVISORS LP
Total Value: $17,626,987,000
Total Holdings: 117
QuarterFilling ID
Q4 250002002654-26-000001
Q3 250002002654-25-000006
Q2 250002002654-25-000004
Q1 250002002654-25-000003
Q4 240002002654-25-000001
Q3 240002002654-24-000005
Q2 240002002654-24-000004
Q1 240002002654-24-000002
Q4 230002002654-24-000001
Q3 230002002654-23-000008
Q2 230002002654-23-000007
Q1 230002002654-23-000006
Q4 220002002654-23-000005
Q3 220002002654-23-000004
Q2 220002002654-23-000003
Q1 220002002654-23-000002
Q4 210002002654-23-000001
Compare Quarter:
NameTitleCUSIPTickerValueSharesShare PriceInvestment% of Portfolio
Seagen Inc.COM81181C104$8,300,65646,912,266SOLE
Incyte CorporationCOM45337C102$2,746,62836,154,117SOLE
BeiGene, Ltd.SPONSORED ADR07725L102$1,888,61111,668,897SOLE
BioMarin Pharmaceutical Inc.COM09061G101$631,5107,620,494SOLE
ACADIA Pharmaceuticals Inc.COM4225108$590,70241,923,486SOLE
Ascendis Pharma A/SSPONSORED ADR04351P101$451,1034,852,655SOLE
argenx SESPONSORED ADR04016X101$424,1781,119,557SOLE
BioCryst Pharmaceuticals, Inc.COM09058V103$134,48012,710,818SOLE
Kodiak Sciences Inc.COM50015M109$132,25217,310,490SOLE
Global Blood Therapeutics, Inc.COM37890U108$119,2533,732,502SOLE
AbCellera Biologics Inc.COM00288U106$111,29410,450,180SOLE
Madrigal Pharmaceuticals, Inc.COM558868105$107,3141,499,213SOLE
Mirati Therapeutics, Inc.COM60468T105$94,6391,409,784SOLE
Immunocore Holdings plcADS45258D105$94,0482,520,730SOLE
Horizon Therapeutics Public Ltd CoSHSG46188101$91,6051,148,504SOLE
Cerus CorporationCOM157085101$84,99716,067,558SOLE
Travere Therapeutics, Inc.COM89422G107$79,9593,300,009SOLE
Replimune Group, Inc.COM76029N106$62,7723,591,081SOLE
Entrada Therapeutics, Inc.COM29384C108$59,2664,865,819SOLE
IGM Biosciences, Inc.COM449585108$56,9053,156,102SOLE
Kymera Therapeutics, Inc.COM501575104$56,7042,879,825SOLE
Krystal Biotech, Inc.COM501147102$53,036807,735SOLE
Prelude Therapeutics Inc.COM74065P101$52,84610,123,824SOLE
Nurix Therapeutics, Inc.COM67080M103$49,1873,882,125SOLE
Legend Biotech CorporationSPONSORED ADS52490G102$47,116856,658SOLE
Alkermes plcSHSG01767105$44,6851,500,000SOLE
ChemoCentryx, Inc.COM16383L106$44,4221,792,657SOLE
Chinook Therapeutics, Inc.COM16961L106$44,3212,534,102SOLE
Insmed IncorporatedCOM PAR $.01457669307$42,5162,156,001SOLE
Immatics N.V.SHSN44445109$38,5314,423,731SOLE
DBV Technologies S.A.SPONSORED ADR23306J101$37,26614,614,264SOLE
Sarepta Therapeutics, Inc.DBCV 1.5% 11/15/2024803607AB6$36,57729,174,000SOLE
Insmed IncorporatedNote 0.75% 6/1/2028457669AB5$33,27840,000,000SOLE
Aerovate Therapeutics, Inc.COM8064107$32,3542,070,010SOLE
Amarin Corporation plcSPONSORED ADR23111206$31,54321,169,805SOLE
Verastem, Inc.COM92337C104$31,30726,988,898SOLE
Ultragenyx Pharmaceutical Inc.COM90400D108$28,098470,974SOLE
2seventy bio, Inc.COMMON STOCK901384107$27,2282,062,744SOLE
Kiniksa Pharmaceuticals, Ltd.COM CL AG5269C101$27,1282,799,577SOLE
Biomea Fusion, Inc.COM09077A106$25,2132,104,559SOLE
Altimmune, Inc.COM02155H200$24,2822,075,403SOLE
Invitae CorporationCOM46185L103$24,0919,873,488SOLE
Pacific Biosciences of California, Inc.COM69404D108$24,0675,444,963SOLE
Xenon Pharmaceuticals Inc.COM98420N105$22,865751,639SOLE
Heron Therapeutics, Inc.COM427746102$22,6878,131,678SOLE
Merus N.V.COMN5749R100$22,536995,397SOLE
Verve Therapeutics, Inc.COM92539P101$21,6451,416,530SOLE
Design Therapeutics, Inc.COM25056L103$20,1131,436,636SOLE
Affimed N.V.COMN01045108$18,2736,596,830SOLE
Instil Bio, Inc.COM45783C101$17,9893,893,700SOLE
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