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0001104659-19-064169
BAKER BROS. ADVISORS LP
Total Value: $14,699,689,000
Total Holdings: 109
QuarterFilling ID
Q4 250002002654-26-000001
Q3 250002002654-25-000006
Q2 250002002654-25-000004
Q1 250002002654-25-000003
Q4 240002002654-25-000001
Q3 240002002654-24-000005
Q2 240002002654-24-000004
Q1 240002002654-24-000002
Q4 230002002654-24-000001
Q3 230002002654-23-000008
Q2 230002002654-23-000007
Q1 230002002654-23-000006
Q4 220002002654-23-000005
Q3 220002002654-23-000004
Q2 220002002654-23-000003
Q1 220002002654-23-000002
Q4 210002002654-23-000001
Compare Quarter:
NameTitleCUSIPTickerValueSharesShare PriceInvestment% of Portfolio
Seattle Genetics, Inc.COM812578102$4,274,89150,057,277SOLE
Incyte CorporationCOM45337C102$2,373,62031,976,557SOLE
ACADIA Pharmaceuticals Inc.COM4225108$1,470,35740,854,586SOLE
BeiGene, Ltd.SPONSORED ADR07725L102$1,442,24611,777,285SOLE
Alexion Pharmaceuticals, Inc.COM15351109$808,7958,258,068SOLE
Amarin Corporation plcSPONSORED ADR23111206$629,81141,544,288SOLE
Genomic Health, Inc.COM37244C101$626,9739,244,665SOLE
BioMarin Pharmaceutical Inc.COM09061G101$511,5187,589,294SOLE
Ascendis Pharma A/SSPONSORED ADR04351P101$326,5513,390,270SOLE
Invitae CorporationCOM46185L103$169,4358,792,678SOLE
Kodiak Sciences Inc.COM50015M109$131,5079,145,116SOLE
Neurocrine Biosciences, Inc.COM64125C109$127,5311,415,283SOLE
argenx SESPONSORED ADR04016X101$116,1891,019,557SOLE
Heron Therapeutics, Inc.COM427746102$111,3356,018,104SOLE
Mirati Therapeutics, Inc.COM60468T105$101,8461,307,220SOLE
Madrigal Pharmaceuticals, Inc.COM558868105$100,8151,169,278SOLE
MyoKardia, Inc.COM62857M105$79,1241,517,237SOLE
Spark Therapeutics, Inc.COM84652J103$72,922751,927SOLE
Tricida, Inc.COM89610F101$60,8111,969,905SOLE
Rhythm Pharmaceuticals, Inc.COM76243J105$58,4702,708,200SOLE
IGM Biosciences, Inc.COM449585108$55,8063,144,000SOLE
Ra Pharmaceuticals, Inc.COM74933V108$55,4712,345,496SOLE
Cerus CorporationCOM157085101$55,41610,749,937SOLE
DBV Technologies S.A.SPONSORED ADR23306J101$47,3825,509,560SOLE
Principia Biopharma Inc.COM74257L108$46,7101,654,029SOLE
Atreca, Inc.CL A Common04965G109$43,2413,532,760SOLE
GW Pharmaceuticals plcADS36197T103$42,658370,845SOLE
Zymeworks Inc.COM98985W102$42,3701,708,472SOLE
Audentes Therapeutics, Inc.COM05070R104$42,3161,506,438SOLE
Neurocrine Biosciences, Inc.NOTE 2.25% 5/15/202464125CAD1$42,11330,770,000SOLE
Insmed IncorporatedCOM PAR $.01457669307$39,3332,229,760SOLE
BioCryst Pharmaceuticals, Inc.COM09058V103$36,45812,725,472SOLE
Adaptive Biotechnologies CorporationCOM00650F109$36,0111,165,411SOLE
Krystal Biotech, Inc.COM501147102$35,9291,034,674SOLE
Neoleukin Therapeutics, Inc.COM64049K104$32,22111,305,679SOLE
CymaBay Therapeutics, Inc.COM23257D103$29,2225,707,411SOLE
Allakos Inc.COM01671P100$26,710339,690SOLE
Kiniksa Pharmaceuticals, Ltd.COM CL AG5269C101$23,8242,799,577SOLE
Merus N.V.COMN5749R100$20,6711,160,014SOLE
uniQure N.V.SHSN90064101$20,377517,700SOLE
UroGen Pharma Ltd.COMM96088105$17,819747,751SOLE
Axsome Therapeutics, Inc.COM05464T104$15,631772,286SOLE
BioMarin Pharmaceutical Inc.NOTE 0.599% 8/1/202409061GAH4$14,72215,000,000SOLE
Xencor, Inc.COM98401F105$14,440428,120SOLE
Aimmune Therapeutics, Inc.COM00900T107$14,112673,908SOLE
Protagonist Therapeutics, Inc.COM74366E102$14,1031,174,282SOLE
La Jolla Pharmaceutical CompanyCOM PAR $.0001 2503459604$13,7211,559,231SOLE
Idera Pharmaceuticals, Inc.COM PAR45168K405$13,3194,608,786SOLE
Aeglea BioTherapeutics, Inc.COM00773J103$13,1781,713,604SOLE
Alkermes plcSHSG01767105$12,194625,030SOLE
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